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Fig. 5. Postoperative blood pressure over 24 h 1 year after the operation ; . Mean 24-h ambulatory blood pressure, 192 128 mmHg, mean heart rate 101 beats min.

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Literature" and to the "pioneering of new and developing fields of technology, making major advancements in traditional fields of engineering, or developing implementing innovative approaches to engineering education." In the past, Dr. Hoffman was recognized by the Society For Biomaterials for his pioneering work and dedication to the field of biomaterials science and engineering by receiving the Clemson Award for contributions to the scientific literature in 1984 and the Founder's Award in 2000. He is a co-author and co-editor of the new edition of Biomaterials Science: An Introduction to Materials in Medicine.

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1. Neerman-Arbez M, Honsberger A, Antonarakis SE, Morris MA. Deletion of the fibrinogen [correction of fibrogen] alpha-chain gene FGA ; causes congenital afibrogenemia. J Clin Invest. 1999; 103: 215-218. Duga S, Asselta R, Santagostino E, et al. Missense mutations in the human beta fibrinogen gene cause congenital afibrinogenemia by impairing fibrinogen secretion. Blood. 2000; 95: 1336-1341. Homer VM, Brennan SO, Ockelford P, George PM. Novel fibrinogen truncation with deletion of Bbeta chain residues 440-461 causes hypofibrinogenaemia. Thromb Haemost. 2002; 88: 427431. Neerman-Arbez M, Vu D, Abu-Libdeh B, Bouchardy I, Morris MA. Prenatal diagnosis for congenital afibrinogenemia caused by a novel nonsense mutation in the FGB gene in a Palestinian family. Blood. 2003; 101: 3492-3494. Asselta R, Spena S, Duga S, et al. Analysis of Iranian patients allowed the identification of the first truncating mutation in the fibrinogen Bbetachain gene causing afibrinogenemia. Haematologica. 2002; 87: 855-859. Maghzal GJ, Brennan SO, Fellowes AP, Spearing R, George PM. Familial hypofibrinogenaemia associated with heterozygous substitution of a conserved arginine residue; Bbeta255 Arg3His Fibrinogen Merivale ; . Biochim Biophys Acta. 2003; 1645: 146-151 and colesevelam.

Muscle Strength Index The Muscle Strength Index MSI ; is a validated measurement of the strength of the muscles of the upper und lower extremity [Stucki 1998, Stucki 1994]. The Muscle Strength Index is calculated as the mean score of standardised isometric extension and flexion strength of the knee and elbow joints and colestipol.
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